WFU

2020年9月19日 星期六

中西醫結合治療對乳腺癌患者預後的影響

與西藥組相比,在中西藥聯合治療後,結果顯示與癌症相關的症狀或癌症治療的副作用(如疲勞、失眠和粘膜炎)有顯著改善。


人參養榮湯可通過補氣養血在2週內改善癌因性疲憊的嚴重程度,還有助於改善睡眠不安、口乾、嗜睡和食慾不振。

紅景天(Rhodiola algida)具有消除餘熱、預防組織損傷和加速傷口癒合的潛力,可減輕粘膜炎。

溫膽湯也被發現可以調節brain–gut axis上的ghrelin,並顯著減少焦慮。

一項retrospective cohort研究發現,加味逍遙散是失眠的推薦處方,並且與降低死亡率顯著相關。

在這項研究中發現,在3個月的西藥治療期間輔助中藥治療是安全的,甚至可以防止RBC降低和肝功能升高。

癌症患者貧血的改善可導致更好的QOL,促進抗癌治療的耐受性和療效,並可能對預後產生影響。

Indeed, the results showed significant improvements in cancer-related symptoms or side effects of cancer treatment such as fatigue, insomnia, and mucositis after intervention in the combined group relative to the Western medicine group.

The efficacy of TCM on breast cancer fatigue has been confirmed in previous studies. Ren Shen Yang Rong Tang (人參養榮湯) was used to improve the severity of cancer-related fatigue within 2 weeks by nourishing qi and blood, and it also helped to ameliorate disturbed sleep, dry mouth, drowsiness, and poor appetite.

Rhodiola algida (紅景天) has the potential to alleviate mucositis by removing residual heat, preventing tissue damage and accelerating wound healing.

Wen Dan Tang (溫膽湯), a formula that is often used clinically to alleviate digestive symptoms such as nausea, belching, and poor appetite, has also been found to regulate ghrelin levels in the brain–gut axis and significantly reduce anxiety.

A retrospective cohort study found that Jia Wei Xiao Yao San (加味逍遙散) was the recommended prescription for insomnia and was significantly associated with reduced mortality.

In this study, it is found that adjuvant TCM therapy during the 3-month Western medicine treatment was safe, and it even prevented the reduction of RBC and the elevation of liver function.  

The improvement of anemia in patients with cancer can lead to better QOL, facilitate the tolerability and efficacy of anticancer treatment, and have a possible impact on prognosis.

https://www.liebertpub.com/doi/full/10.1089/acm.2019.0200

*此篇論文發表在2020年The Journal of Alternative and Complementary Medicine

Lee, Y. C., Chen, Y. H., Huang, Y. C., Lee, Y. F., & Tsai, M. Y. (2020). Effectiveness of Combined Treatment with Traditional Chinese Medicine and Western Medicine on the Prognosis of Patients with Breast Cancer. The Journal of Alternative and Complementary Medicine26(9), 833-840.